Uplizna® (Inebilizumab-cdon) IV Infusion Therapy

Specialized Therapy for Neuromyelitis Optica Spectrum Disorder (NMOSD)

Clearwell Infusion Centers offers Uplizna infusion therapy for patients diagnosed with NMOSD. At our Miami facility, we combine advanced clinical oversight with a spa-like environment, ensuring a comfortable and efficient experience for patients who require long-term biologic infusions.

What Is Uplizna?

Uplizna® (inebilizumab-cdon) is an FDA-approved monoclonal antibody therapy used to treat adults with neuromyelitis optica spectrum disorder (NMOSD) who are anti-AQP4 antibody positive. It works by targeting CD19-expressing B cells, which play a key role in triggering inflammatory attacks on the optic nerves and spinal cord in NMOSD. Uplizna is administered as an IV infusion. Patients receive an initial dose split into two infusions two weeks apart, followed by a single infusion every six months.

Learn more at the official Uplizna website.

Condition Treated with Uplizna

Uplizna is indicated for the treatment of:

• Neuromyelitis Optica Spectrum Disorder (NMOSD) in adults who are anti-AQP4 antibody positive

By reducing the frequency and severity of relapses, Uplizna helps preserve vision, mobility, and quality of life for patients with this rare autoimmune condition.

Uplizna Side Effects

Uplizna is generally well tolerated but may cause:

• Infusion-related reactions
• Urinary tract infections
• Headache
• Joint pain
• Nausea
• Lower respiratory tract infections

Vaccination against hepatitis B and screening for tuberculosis are recommended prior to starting treatment. At Clearwell, we follow strict ACHC-accredited safety protocols to ensure close monitoring during and after each infusion.

For full safety information, visit the Uplizna Prescribing Information.

Why Choose Clearwell for Your Uplizna Infusion?

Clearwell Infusion Centers is committed to delivering compassionate and professional care in a relaxing outpatient setting. When you receive Uplizna at our Miami center, you’ll benefit from:

• Private treatment suites with spa-like amenities
• Low patient-to-nurse ratio for attentive care
• Flexible appointment times, including weekends and evenings
• Comprehensive insurance coordination, including prior authorizations and benefits checks
• ACHC-accredited facility and safety standards
• Close coordination with your prescribing provider and care team

Uplizna infusions take approximately 90 minutes, followed by a monitoring period to ensure safety and tolerance.

Getting Started with Uplizna

If your provider has prescribed Uplizna, we will manage every step of your treatment journey—from insurance coordination to scheduling and follow-up care. Our team ensures a smooth, patient-friendly experience at every visit.

Have questions? Call us at 305‑306‑7147 or email contact@clearwellinfusion.com.

Referring Providers: Partner with Clearwell Infusion Centers

We collaborate with neurologists and MS specialists across South Florida to provide expert administration of Uplizna in a trusted outpatient environment.

Why refer to Clearwell?

• Fast benefit verification and prior authorization turnaround
• Seamless referral intake and same-week scheduling
• Clinical documentation sent promptly to your office
• Expert staff experienced in NMOSD and neurologic biologics
• ACHC-accredited protocols for consistent patient safety

To refer a patient for Uplizna infusion therapy in Miami, email referrals@clearwellinfusion.com or call 305‑306‑7147.

Looking to start your Uplizna treatment at Clearwell Infusion Centers?

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