Ruxience® (Rituximab-pvvr) IV Infusion Therapy

A Cost-Effective Rituxan® Biosimilar for Autoimmune Conditions and Blood Cancers

Clearwell Infusion Centers offers Ruxience IV therapy for patients managing autoimmune disorders or hematologic cancers. Located in Miami, our infusion center provides private suites, personalized care, and flexible appointment options—ensuring patients receive their treatments safely and comfortably.

What Is Ruxience?

Ruxience® (rituximab-pvvr) is an FDA-approved biosimilar to Rituxan® (rituximab), a monoclonal antibody that targets CD20-positive B cells, which are responsible for driving inflammation in autoimmune diseases and proliferation in certain cancers. Ruxience works by reducing or eliminating these cells to help control disease activity.

As a biosimilar, Ruxience has no clinically meaningful differences from Rituxan in terms of safety, purity, and potency—offering a high-quality alternative with potential cost advantages.

Learn more at the official Ruxience website.

Conditions Treated with Ruxience

Ruxience is indicated for use in:

• Rheumatoid Arthritis (RA) – in combination with methotrexate
• Granulomatosis with Polyangiitis (GPA)
• Microscopic Polyangiitis (MPA)
• Non-Hodgkin’s Lymphoma (NHL)
• Chronic Lymphocytic Leukemia (CLL)

Ruxience is commonly prescribed when other treatments have been ineffective or not well tolerated.

Ruxience Side Effects

As with any biologic therapy, side effects may occur. The most common include:

• Infusion-related reactions (fever, chills, rash)
• Headache or fatigue
• Upper respiratory infections
• Low white blood cell counts
• Increased risk of serious infections (e.g., hepatitis B reactivation, PML)

Clearwell follows ACHC-accredited clinical safety protocols, with premedication and monitoring in place to minimize risk during your infusion.

For complete safety information, view the Ruxience prescribing info.

Why Choose Clearwell for Your Ruxience Infusion?

Clearwell Infusion Centers is designed for comfort, safety, and convenience. When you receive Ruxience therapy with us, you’ll benefit from:

• Private treatment suites with spa-like amenities
• Low patient-to-nurse ratio for attentive care
• Flexible appointment times, including weekends and evenings
• Comprehensive insurance coordination, including prior authorizations and benefits checks
• ACHC-accredited facility and safety standards
• Close coordination with your prescribing provider and care team

Ruxience infusion duration varies depending on diagnosis and protocol but typically ranges from 90 minutes to several hours.

Getting Started with Ruxience

If you’ve been prescribed Ruxience, we’ll work directly with your provider and insurance to ensure a smooth start. Our team will help schedule your appointment, manage authorizations, and support you every step of the way.

Have questions? Call 305‑306‑7147 or email contact@clearwellinfusion.com.

Referring Providers: Partner with Clearwell Infusion Centers

Clearwell works closely with specialists across South Florida to deliver safe and effective administration of biosimilars like Ruxience.

Why refer to Clearwell?

• Fast turnaround for benefits verification and prior authorizations
• Streamlined, low-burden referral process
• Timely clinical updates and infusion summaries sent to your office
• Trained infusion staff with biosimilar experience
• ACHC-accredited compliance and safety protocols

To refer a patient for Ruxience IV infusion in Miami, email referrals@clearwellinfusion.com or call 305‑306‑7147.

Looking to start your Ruxience treatment at Clearwell Infusion Centers?

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