Ultomiris® (Ravulizumab-cwvz) IV Infusion Therapy

Long-Acting Treatment for PNH, aHUS, and Generalized Myasthenia Gravis

Clearwell Infusion Centers offers Ultomiris IV infusion therapy for patients with paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and generalized myasthenia gravis (gMG). At our Miami-based center, patients receive high-quality care in a comfortable, private, and flexible outpatient setting.

What Is Ultomiris?

Ultomiris® (ravulizumab-cwvz) is an FDA-approved, long-acting complement C5 inhibitor that reduces immune-mediated damage caused by uncontrolled complement activation. It offers extended dosing intervals compared to Soliris®, with infusions required every 8 weeks after the initial loading dose.

Ultomiris is administered via intravenous infusion and requires ongoing monitoring during treatment.

Learn more at the official Ultomiris website.

Conditions Treated with Ultomiris

Ultomiris is indicated for the treatment of:

• Paroxysmal Nocturnal Hemoglobinuria (PNH)
• Atypical Hemolytic Uremic Syndrome (aHUS)
• Generalized Myasthenia Gravis (gMG) in adults who are anti-AChR antibody positive

Ultomiris improves symptoms by preventing the destruction of red blood cells and reducing inflammation linked to complement overactivation.

Ultomiris Side Effects

Common side effects may include:

• Headache
• Upper respiratory tract infections
• Diarrhea or nausea
• Infusion-related reactions
• Fatigue
• Increased risk of meningococcal infection (vaccination required)

Clearwell’s clinical team monitors all patients closely during and after infusions, using ACHC-accredited protocols to ensure patient safety and comfort.

For full safety information, visit the Ultomiris Prescribing Information.

Why Choose Clearwell for Your Ultomiris Infusion?

Clearwell Infusion Centers provides a supportive and streamlined experience for complex biologic treatments. When you choose Clearwell in Miami for your Ultomiris infusions, you benefit from:

• Private treatment suites with spa-like amenities
• Low patient-to-nurse ratio for attentive care
• Flexible appointment times, including weekends and evenings
• Comprehensive insurance coordination, including prior authorizations and benefits checks
• ACHC-accredited facility and safety standards
• Close coordination with your prescribing provider and care team

Ultomiris is typically infused over 2 hours for adults and every 8 weeks following a loading dose.

Getting Started with Ultomiris

If your specialist has prescribed Ultomiris, we’ll coordinate the entire process—from benefits verification to scheduling and long-term treatment planning.

Call us at 305‑306‑7147 or email contact@clearwellinfusion.com to get started.

Referring Providers: Partner with Clearwell Infusion Centers

We collaborate with hematologists, nephrologists, and neurologists across South Florida to deliver Ultomiris therapy in a trusted outpatient setting.

Why refer to Clearwell?

• Rapid benefits verification and prior authorization support
• Streamlined referral process and same-week scheduling
• Timely clinical documentation and communication
• Experienced staff trained in complement inhibitor therapies
• ACHC-accredited care environment

To refer a patient for Ultomiris infusion in Miami, contact referrals@clearwellinfusion.com or call 305‑306‑7147.

Looking to start your Ultomiris treatment at Clearwell Infusion Centers?

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