Tysabri® (Natalizumab) IV Infusion Therapy

Targeted Therapy for Multiple Sclerosis and Crohn’s Disease

Clearwell Infusion Centers offers Tysabri IV infusion therapy for patients with relapsing forms of multiple sclerosis (MS) and moderate to severe Crohn’s disease. Our Miami infusion center is designed to provide a comfortable, private, and efficient experience—with flexible scheduling, experienced staff, and ACHC-accredited safety protocols.

What Is Tysabri?

Tysabri® (natalizumab) is an FDA-approved monoclonal antibody that works by blocking immune cells from entering the brain, spinal cord, and gut, reducing inflammation and disease activity. It is used when other treatments haven’t worked or as an escalation option for patients who need more effective control.

Tysabri is administered as an IV infusion once every 4 weeks, and requires enrollment in a REMS (Risk Evaluation and Mitigation Strategy) program due to its rare but serious risk of progressive multifocal leukoencephalopathy (PML).

Learn more at the official Tysabri website.

Conditions Treated with Tysabri

Tysabri is indicated for:

• Relapsing Forms of Multiple Sclerosis (MS)
• Moderate to Severe Crohn’s Disease (when standard therapies have failed)

Tysabri helps reduce MS relapses and MRI-detected disease activity. In Crohn’s disease, it may induce and maintain remission by reducing inflammation in the gastrointestinal tract.

Tysabri Side Effects

While generally well tolerated, Tysabri can cause:

• Headache
• Fatigue
• Joint pain
• Nausea
• Infusion-related reactions
• Increased risk of infections, including PML (a rare brain infection)

At Clearwell, our team follows strict REMS protocols and ACHC-accredited procedures to monitor for side effects and ensure patient safety during and after infusions.

For full safety information, see the Tysabri Prescribing Information.

Why Choose Clearwell for Your Tysabri Infusion?

Patients choose Clearwell Infusion Centers in Miami for Tysabri therapy because we offer:

• Private treatment suites with spa-like amenities
• Low patient-to-nurse ratio for attentive care
• Flexible appointment times, including weekends and evenings
• Comprehensive insurance coordination, including prior authorizations and benefits checks
• ACHC-accredited facility and safety standards
• Close coordination with your prescribing provider and care team

Tysabri infusions typically take about 1 hour, with a post-infusion observation period of at least 1 hour for safety.

Getting Started with Tysabri

If your specialist has prescribed Tysabri, Clearwell will coordinate all aspects of your care—from insurance approvals to REMS enrollment and appointment scheduling.

Call 305‑306‑7147 or email contact@clearwellinfusion.com to begin treatment.

Referring Providers: Partner with Clearwell Infusion Centers

We work with neurologists, gastroenterologists, and MS clinics across South Florida to administer Tysabri safely and efficiently.

Why refer your patients to Clearwell?

• Fast prior auth and REMS enrollment support
• Simple referral process and same-week scheduling
• Timely clinical documentation sent to your office
• Experienced nursing staff trained in MS and GI biologics
• ACHC-accredited clinical oversight and safety standards

To refer a patient for Tysabri infusion in Miami, contact our provider team at referrals@clearwellinfusion.com or call 305‑306‑7147.

Looking to start your Tysabri treatment at Clearwell Infusion Centers?

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