Benlysta® (Belimumab) IV Infusion Therapy

Specialized Treatment for Lupus and Autoimmune Disease

Clearwell Infusion Centers offers safe, comfortable, and efficient administration of Benlysta (belimumab) for patients with systemic lupus erythematosus (SLE) and lupus nephritis. As a trusted infusion center in Miami, we provide private suites, flexible scheduling, and a supportive, patient-focused experience.

What Is Benlysta?

Benlysta® (belimumab) is an FDA-approved biologic medication used to treat systemic lupus erythematosus (SLE) and lupus nephritis. It is a monoclonal antibody that targets and blocks the B-lymphocyte stimulator (BLyS), a protein that plays a central role in autoimmune activity. By lowering abnormal B-cell activity, Benlysta helps reduce flares, improve symptoms, and slow disease progression.

Benlysta is available as both a subcutaneous injection and intravenous (IV) infusion. At Clearwell, we administer the IV formulation, typically every 4 weeks after initial loading doses.

Conditions Treated with Benlysta

Benlysta is approved for use in patients with:

• Systemic Lupus Erythematosus (SLE)
• Lupus Nephritis (in combination with standard therapy)

Benlysta is generally prescribed for patients who continue to experience disease activity despite other lupus treatments.

Benlysta Side Effects

As with any biologic therapy, Benlysta may cause side effects.

Common side effects:

• Nausea or diarrhea
• Headache
• Fatigue
• Insomnia
• Fever
• Depression or mood changes
• Infusion-related reactions (chills, rash, itching, shortness of breath)

Our clinical team will monitor for any side effects and communicate with your referring provider to ensure a safe and effective treatment experience.

For a full list of potential side effects, please see the Important Safety Information and Medication Guide on the Benlysta website.

Getting Started with Benlysta Treatment

If you’ve been diagnosed with lupus or lupus nephritis and prescribed Benlysta, Clearwell Infusion Centers will work closely with your provider to coordinate your care, verify insurance benefits, and get your treatment started quickly and smoothly.

Questions? Call us at 305‑306‑7147 or email contact@clearwellinfusion.com.

For Physicians and Referring Providers

Clearwell Infusion Centers works with rheumatologists, nephrologists, and internal medicine providers to safely administer Benlysta therapy.

Why refer your patients to Clearwell?

• Fast turnaround for insurance approvals and benefit checks
• Easy referral process and same-week scheduling
• Clinical documentation and follow-up sent to your office
• Trusted administration of FDA-approved, non-compounded Remicade
• ACHC-accredited and compliant with all safety protocols

To refer a patient for Benlysta infusion therapy in Miami, contact our provider team at referrals@clearwellinfusion.com or call 305‑306‑7147.

Looking to start your Benlysta treatment at Clearwell Infusion Centers?

Fill out the form below and a member of our team will contact you