Saphnelo® (Anifrolumab-fnia) IV Infusion Therapy

Innovative Biologic Therapy for Systemic Lupus Erythematosus (SLE)

Clearwell Infusion Centers offers Saphnelo infusion therapy for adults living with systemic lupus erythematosus (SLE). Located in Miami, our center provides private infusion suites, compassionate care, and flexible scheduling to make treatment more accessible and comfortable.

What Is Saphnelo?

Saphnelo® (anifrolumab-fnia) is an FDA-approved monoclonal antibody used to treat adults with moderate to severe systemic lupus erythematosus. It works by blocking the type I interferon receptor, a key pathway involved in lupus inflammation and immune system overactivity.

Saphnelo is administered as a monthly IV infusion and is designed to be used alongside standard lupus therapies, such as antimalarials or corticosteroids.

Learn more at the official Saphnelo website.

Condition Treated with Saphnelo

Saphnelo is indicated for:

• Systemic Lupus Erythematosus (SLE) in adults receiving standard therapy

It is not approved for patients with severe active lupus nephritis or central nervous system lupus.

Saphnelo Side Effects

Saphnelo is generally well tolerated, but potential side effects may include:

• Upper respiratory infections
• Headache
• Nausea
• Infusion-related reactions (dizziness, chills, rash)
• Herpes zoster (shingles)

At Clearwell, all infusions are administered by experienced nursing staff under ACHC-accredited safety protocols, with pre- and post-infusion monitoring to ensure your well-being.

View full safety details in the Saphnelo prescribing information.

Why Choose Clearwell for Your Saphnelo Infusion?

At Clearwell Infusion Centers, we’re committed to delivering a safe, supportive, and patient-first experience. When you choose us for your Saphnelo treatment, you benefit from:

• Private treatment suites with spa-like amenities
• Low patient-to-nurse ratio for attentive care
• Flexible appointment times, including weekends and evenings
• Comprehensive insurance coordination, including prior authorizations and benefits checks
• ACHC-accredited facility and safety standards
• Close coordination with your prescribing provider and care team

Each Saphnelo infusion typically takes about 30 minutes, with monthly treatment intervals.

Getting Started with Saphnelo

If your provider has recommended Saphnelo for lupus management, our team will handle the details—from insurance approvals to appointment scheduling—to make your treatment journey smooth and stress-free.

Call us at 305‑306‑7147 or email contact@clearwellinfusion.com to get started.

Referring Providers: Partner with Clearwell Infusion Centers

Clearwell works closely with rheumatologists and autoimmune specialists across South Florida to deliver high-quality Saphnelo infusion therapy in a safe outpatient setting.

Why refer to Clearwell?

• Fast turnaround on authorizations and benefit checks
• Streamlined referral and intake process
• Prompt clinical communication and patient updates
• Experienced infusion nurses trained in lupus therapies
• ACHC-accredited compliance and safety standards

To refer a patient for Saphnelo infusions in Miami, email referrals@clearwellinfusion.com or call 305‑306‑7147.

Looking to start your Saphnelo treatment at Clearwell Infusion Centers?

Fill out the form below and a member of our team will contact you