Advanced Treatment for Hereditary ATTR Amyloidosis

Clearwell Infusion Centers offers safe, comfortable, and efficient administration of Amvuttra (vutrisiran) for patients with hereditary ATTR (hATTR) amyloidosis. As a leading infusion and injection center in Miami, we provide private suites, flexible scheduling, and a supportive, patient-first environment.

What Is Amvuttra?

Amvuttra® (vutrisiran) is an FDA-approved RNA interference (RNAi) therapy designed to treat polyneuropathy caused by hereditary transthyretin-mediated amyloidosis (hATTR). It works by silencing the gene responsible for producing abnormal transthyretin (TTR) protein, which builds up in nerves and organs, leading to progressive damage.

Amvuttra is administered via a quick subcutaneous injection once every 3 months, offering an effective and convenient treatment option for eligible patients.

Conditions Treated with Amvuttra

Amvuttra is approved to treat:

• Polyneuropathy related to TTR protein buildup
• Hereditary ATTR (hATTR) amyloidosis

Patients with this rare genetic condition may experience symptoms such as:

• Numbness or tingling in the hands and feet
• Muscle weakness or pain
• Balance or coordination issues
• Gastrointestinal or cardiovascular complications

Amvuttra may help slow disease progression and improve quality of life.

Side Effects and Safety

Like all medications, Amvuttra may cause side effects. Common side effects may include:

• Injection site reactions (redness, pain, swelling)
• Joint or muscle pain
• Fatigue
• Low levels of vitamin A (your provider may recommend supplements)

Our clinical team will monitor for any side effects and communicate with your referring provider to ensure a safe and effective treatment experience.

For a full list of potential side effects, please see the Important Safety Information and Medication Guide on the official Amvuttra website.

Why Choose Clearwell for Your Amvuttra Infusion?

Our Miami-based infusion center is designed with patient comfort, safety, and accessibility in mind. When you receive Remicade IV treatment at Clearwell, you’ll benefit from:

• Private treatment suites with spa-like amenities
• Low patient-to-nurse ratio for attentive care
• Flexible appointment times, including weekends and evenings
• Comprehensive insurance coordination, including prior authorizations and benefits checks
• ACHC-accredited facility and safety standards
• Close coordination with your prescribing provider and care team

Amvuttra IV infusions are typically given every 4 weeks, depending on your specific diagnosis and clinical response.

Starting Amvuttra Therapy

If you have a qualifying condition and are considering Remicade therapy, speak with your healthcare provider. We’re happy to coordinate with your doctor, answer insurance questions, and ensure a smooth start to treatment.

Questions? Call us at 305‑306‑7147 or email contact@clearwellinfusion.com.

For Physicians and Referring Providers

Clearwell partners with rheumatologists, pediatricians, and hospital teams across South Florida to deliver safe, efficient Actemra infusions.

Why refer your patients to Clearwell?

• Fast turnaround for insurance approvals and benefit checks
• Easy referral process and same-week scheduling
• Clinical documentation and follow-up sent to your office
• Trusted administration of FDA-approved, non-compounded Remicade
• ACHC-accredited and compliant with all safety protocols

To refer a patient for Remicade infusion in South Florida, contact our provider team at contact@clearwellinfusion.com or call 305‑306‑7147.