Targeted Treatment for Sickle Cell Disease

Clearwell Infusion Centers offers high-quality, comfortable, and efficient administration of Adakveo (crizanlizumab) for patients with sickle cell disease. As a leading infusion center in Miami, we provide private suites, flexible scheduling, and a supportive, patient-first environment.

What Is Adakveo?

Adakveo® (crizanlizumab) is an FDA-approved monoclonal antibody used to reduce the frequency of pain crises (vaso-occlusive crises) in patients with sickle cell disease. It works by targeting P-selectin, a protein that plays a key role in the inflammation and cell clumping that leads to pain episodes.

Adakveo is administered as a monthly intravenous (IV) infusion and is typically used alongside other sickle cell treatments to reduce painful episodes and improve quality of life.

Conditions Treated with Adakveo Infusions

Adakveo is approved to treat:

• Sickle Cell Disease (SCD)
• Recurrent vaso-occlusive pain crises (VOCs)

Sickle cell disease can lead to:

• Episodes of severe pain
• Organ damage
• Frequent hospitalizations
• Decreased quality of life

Adakveo may help reduce the number of crises and hospital visits for patients living with this chronic condition.

Adakveo Side Effects

As with any medication, side effects are possible. Common side effects may include:

• Nausea
• Joint pain (arthralgia)
• Fever
• Fatigue
• Headache
• Back pain
• Infusion-related reactions

Our clinical team will monitor for any side effects and communicate with your referring provider to ensure a safe and effective treatment experience.

For a full list of potential side effects, please see the Important Safety Information and Medication Guide on the Adakveo website.

Why Choose Clearwell for Your Adakveo Infusion?

Our Miami-based infusion center is designed with patient comfort, safety, and accessibility in mind. When you receive Adakveo IV treatment at Clearwell, you’ll benefit from:

• Private treatment suites with spa-like amenities
• Low patient-to-nurse ratio for attentive care
• Flexible appointment times, including weekends and evenings
• Comprehensive insurance coordination, including prior authorizations and benefits checks
• ACHC-accredited facility and safety standards
• Close coordination with your prescribing provider and care team

Adakveo infusions are given monthly and typically take about 30 to 60 minutes.

Getting Started with Adakveo Treatment

If you have sickle cell disease and experience frequent pain crises, talk to your provider about whether Adakveo is right for you. Clearwell Infusion Centers can help coordinate your care, handle insurance approvals, and schedule your infusions with ease.

Questions? Call us at 305‑306‑7147 or email contact@clearwellinfusion.com.

For Physicians and Referring Providers

We work closely with hematologists and primary care physicians across South Florida to deliver consistent, high-quality Adakveo infusion therapy.

Why refer your patients to Clearwell?

• Fast turnaround for insurance approvals and benefit checks
• Easy referral process and same-week scheduling
• Clinical documentation and follow-up sent to your office
• Trusted administration of FDA-approved medications
• ACHC-accredited and compliant with all safety protocols

To refer a patient for Adakveo infusion in Miami, contact our provider team at referrals@clearwellinfusion.com or call 305‑306‑7147.